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Vesicle associated membrane proteins (VAMP) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion. * VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neuromediator release. * VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles. * VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis. * * VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures. * * VAMP7 is found both in secretory granules and endosomes. * VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells. *VAMP4 is involved in transport from the Golgi. ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Vesicle-associated membrane protein」の詳細全文を読む スポンサード リンク
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